Johan Flygare Selected Research

Phosphotransferases (Kinase)

1/2021	The active component of ginseng, ginsenoside Rb1, improves erythropoiesis in models of Diamond-Blackfan anemia by targeting Nemo-like kinase.
11/2020	Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond-Blackfan anemia through induction of miR-26a.

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Johan Flygare Research Topics

Disease

17	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan) 01/2022 - 05/2003
9	Anemia 11/2020 - 07/2010
5	Bone Marrow Failure Disorders 01/2019 - 12/2011
2	Neoplasms (Cancer) 10/2020 - 09/2019
2	Inflammation (Inflammations) 12/2011 - 07/2010
1	Vomiting 01/2023
1	Albuminuria 01/2023
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2023
1	Nausea 01/2023
1	Hemolysis 01/2021
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 11/2020
1	Type 2 Diabetes Mellitus (MODY) 11/2020
1	Pre-Eclampsia (Preeclampsia) 09/2020
1	Wounds and Injuries (Trauma) 09/2020
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 09/2020
1	Hemorrhage 09/2020
1	Atherosclerosis 09/2020
1	Osteolysis 09/2019
1	Hypoxia (Hypoxemia) 03/2011
1	Congenital Hypoplastic Anemia 11/2008

Drug/Important Bio-Agent (IBA)

10	Ribosomal Proteins (Ribosomal Protein)IBA 01/2021 - 02/2007
7	ribosomal protein S19IBA 01/2017 - 05/2003
3	Heme (Haem)IBA 01/2022 - 09/2020
3	GlucocorticoidsIBA 12/2011 - 07/2010
2	Proteins (Proteins, Gene)FDA Link 01/2023 - 11/2020
2	Phosphotransferases (Kinase)IBA 01/2021 - 11/2020
2	Hemoglobins (Hemoglobin)IBA 01/2021 - 09/2012
2	Erythropoietin FDA Link 03/2011 - 07/2010
2	Small Interfering RNA (siRNA)IBA 06/2005 - 04/2005
1	Radioisotopes (Radionuclides)IBA 01/2023
1	Amino Acids FDA Link 01/2023
1	Peptide Receptors (Peptide Receptor)IBA 01/2023
1	lutetium Lu 177 dotatateIBA 01/2023
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2021
1	6- hydroxy- 2,5,7,8- tetramethylchroman- 2- carboxylic acid (Trolox)IBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2021
1	Reducing AgentsIBA 01/2021
1	ginsenoside Rb1IBA 01/2021
1	Heme-Binding ProteinsIBA 01/2021
1	HemopexinIBA 01/2021
1	Vitamin E FDA LinkGeneric 01/2021
1	HematinicsIBA 11/2020
1	Metformin (Glucophage)FDA LinkGeneric 11/2020
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 10/2020
1	Protein Subunits (Protein Subunit)IBA 10/2020
1	Therapeutic UsesIBA 09/2020
1	GlobinsIBA 01/2017
1	Peptide Elongation Factors (Elongation Factor)IBA 01/2017
1	DiamondIBA 11/2015
1	Leucine (L-Leucine)FDA Link 09/2012
1	Fibronectins (Fibronectin)IBA 07/2010

Therapy/Procedure

2	Therapeutics 01/2023 - 09/2019
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2021
1	Blood Transfusion (Blood Transfusions) 09/2020
1	Transplantation 11/2008